Royal Caribbean

Odyssey of the Seas

Built 2021

Greek Isles & Italy Cruise

Oct 18, 2026 - Oct 25, 20267 nights

RoundtripRoundtrip from Rome

Cabin from $3,872(Interior)

Solo from $3,302(Balcony)

Cabin updated under 1h agoSolo updated under 1h ago

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Cabin Prices

Cabin2 SailorsSolo

Balcony

Sold out

$3,302

Interior

$3,872

Sold out

Ocean View

$4,350

Sold out

Royal Suite Class

Sold out

Per cabin · before taxes & fees

2 sailors on cruise line site Solo on cruise line site

Schedule

October 2026

November 2026

Columbus Day

WeekendHolidaySailing

Route map

6 stops

RomeMessinaSantoriniMykonosNaplesRome

Comments

Things to Do

Rome

Must See

Colosseum

4.8 (483,501)

Ancient amphitheater for gladiator battles, day trip from port via train/shuttle. Iconic Rome must-see. Book skip-the-line.

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Must See

Pantheon

4.8 (274,195)

Perfectly preserved Roman temple with oculus dome. Free entry. Architectural marvel.

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Must See

Vatican Museums & Sistine Chapel

4.7 (91,701)

Michelangelo's ceiling and endless art treasures. Full-day excursion required. Spiritual pinnacle.

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Popular

Trevi Fountain

4.7 (496,354)

Baroque fountain where you toss coins for return to Rome. Crowded but magical. Toss from your cruise bucket list.

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Messina

Must See

Messina Cathedral

4.7 (7,047)

Norman-Byzantine gem with bell tower that performs daily automata show. Rich mosaics inside.

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Must See

Fountain of Orion

4.4 (1,105)

Senatorial palace square fountain depicting Orion legend. Iconic photo spot.

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Popular

Regional Museum

4.5 (1,584)

Artifacts from ancient Messina earthquakes. Insight into Sicilian history.

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Popular

Excursion to Taormina

5.0 (53)

Ancient theater with Etna volcano views. Popular cruise day trip.

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Santorini

Must See

Boat Tour to Nea Kameni Volcano

4.5 (8)

Hike active crater and hot springs soak on classic caldera circuit. 3-4 hour tenders from Fira.

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Must See

Fira Town

Cable car down to old port, shop jewelry, and dine clifftop with volcano views. Lively hub steps from tender dock.

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Must See

Oia Village

Wander blue-domed churches and whitewashed Caldera cliffs at the postcard-perfect sunset spot. Bus or taxi from Fira/Athens.

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Popular

Akrotiri Archaeological Site

4.4 (11,387)

Walk Minoan ruins preserved by volcanic ash like Pompeii, with advanced plumbing. Guided tours recommended.

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Mykonos

Must See

Windmills of Kato Mili

4.6 (6,156)

Iconic 16th-century mills overlooking sea. Sunset photos.

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Must See

Little Venice

Picturesque quarter with cafes over water. Windmill adjacency.

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Popular

Paradise Beach

3.9 (939)

Party beach with DJs and umbrellas. Full-day vibe.

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Popular

Delos Island

4.7 (443)

Uninhabited archaeological site ferry ride. Apollo birthplace.

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Naples

Must See

Mount Vesuvius

4.3 (8,132)

Hike active volcano crater with bay views. Strenuous add-on. Dramatic summit.

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Must See

Pompeii

Frozen Roman city buried by Vesuvius. Guided excursion essential. Time-capsule wonder.

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Popular

Naples National Archaeological Museum

4.6 (35,833)

Pompeii artifacts, mosaics, and sculptures. Downtown. Treasure trove.

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Popular

Castel Nuovo

4.4 (34,958)

Medieval fortress with triumphal arch. Waterfront. Moated majesty.

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